Innovation and Technology Transfer

This page is aimed at both industry and academia and contains details of Innovation and Technology Transfer activities resulting from the AEROPATH project.

AEROPATH Target Database

The AEROPATH Target Database aids the identification of potential drug targets from the genome of Pseudomonas aeruginosa, an important Gram negative pathogen. Target assessment is achieved by coupling a chemistry-led approach to predicting target druggability with information on gene essentiality, virulence factors, predicted selectivity, related bacterial orthologs and assessment of structural biology accessibility. Information from a range of sources is integrated into an Oracle relational database with a web framework that enables the proteome to be sorted and filtered by a range of criteria and for each target to be explored in depth. The database will be updated throughout the duration of the AEROPATH project to incorporate new information. The database is available at http://aeropath.lifesci.dundee.ac.uk/.