Publications and Presentations

This page includes

• Scientific Papers published as a result of this project
• Conference Presentations about the project
• Project Materials and General Interest

Scientific Papers

• Nucleophilic catalysis of acylhydrazone equilibration for protein-directed dynamic covalent chemistry by Venugopal T. Bhat,Anne M. Caniard,Torsten Luksch,Ruth Brenk,Dominic J. Campopiano and Michael F. Greaney published in Nature Chemistry, June 2010, Volume 2 No. 6 (pp490-497)
• The Scottish Structural Proteomics Facility: targets, methods and outputs by Muse Oke, Lester G. Carter, Kenneth A. Johnson, Huanting Liu, Stephen A. McMahon, Xuan Yan, Melina Kerou, Nadine D. Weikart, Nadia Kadi, Md. Arif Sheikh, Stefan Schmelz, Mark Dorward, Michal Zawadzki, Christopher Cozens, Helen Falconer, Helen Powers, Ian M. Overton, C. A. Johannes van Nieker, Xu Peng, Prakash Patel, Roger A. Garrett, David Prangishvili Catherine H. Botting, Peter J. Coote, David T. F. Dryden, Geoffrey J. Barton, Ulrich Schwarz-Linek, Gregory L. Challis, Garry L. Taylor, Malcolm F. White and James H. Naismith published in Journal of Structural and Functional Genomics, Volume 11, Number 2 / June, 2010, pages 167-180 (open access)
• Specificity and Mechanism of Acinetobacter baumanii Nicotinamidase: Implications for Activation of the Front-Line Tuberculosis Drug Pyrazinamide by Dr. Paul K. Fyfe, Vincenzo A. Rao, Aleksandra Zemla, Dr. Scott Cameron, Prof. William N. Hunter published in Angewandte Chemie International Edition, Volume 48, Issue 48, Pages 9176 - 9179

Conference Presentations

• The AEROPATH project: Identification, characterisation and exploitation of novel Gram-negative drug targets, by Robert Schnell, Tatyana Sandalova, Jolanta Kopec, Jason Schmidberger and Gunter Schneider, presented at the 14th Annual SBNet meeting, Tällberg, Sweden, (June 11-14th 2010)
• A structure-based model for the prediction of protein druggability, poster by Daniel Muthas, Agata Krasowski and Ruth Brenk, presented at “New Approaches in Drug Design and Discovery” International Workshop, Marburg, Germany (March 22nd-25th 2010)
• What is a Drug Target? Development of a Molecular Interaction Ontology, by R. Bickerton, presented at Bio-IT World, Hannover (October 6-8th 2009). Part 1 (Chemogenomics), Part 2 (What is an Ontology?), Part 3 (Aeropath project)
• New research to target gram negative bacteria, poster by M. Maringer, C. Huck, W. Oehlmann, M. Singh and B. Lecher, presented at 47th annual meeting of the society for laboratory animal science GV-SOLAS, Vienna (September 13-15th 2009)
• Aeropath: An EU Consortium for Characterization and Exploitation of Novel Gram-Negative Drug Targets presented by Bill Hunter at ELRIG Drug Discovery 2009 (September 7-8th 2009)
• An Overview of AEROPATH presented by Bill Hunter at “The Challenge of Antibacterial Drug Development” Conference in San Diego, California (March 18-19th 2009)

Project Materials and General Interest

• Drug Discovery in Dundee: A Q&A with Andrew Hopkins (WP3 Leader) published in Bio-IT World, January - February 2010 Edition
• Structure-based Ligand Design and the Promise Held for Antiprotozoan Drug Discovery by Bill Hunter (Project Coordinator) published in the Journal of Biological Chemistry, May 1, 2009